Is low serum bilirubin an independent risk factor for coronary artery disease in men but not in women?

نویسندگان

  • Georg Endler
  • Ahmad Hamwi
  • Raute Sunder-Plassmann
  • Markus Exner
  • Thomas Vukovich
  • Christine Mannhalter
  • Johann Wojta
  • Kurt Huber
  • Oswald Wagner
چکیده

chiatry 2002;26:197–9. 10. Schoonman GG, Wiendels NJ, Ferrari MD. Gabapentin in migraine prophylaxis: is it effective and well tolerated? Headache 200;42:235. 11. Jeffery SM, Pepe JJ, Popvich LM, Vitagliano G. Gabapentin for hot flashes in prostate cancer. Ann Pharmacother 2002;36:433–6. 12. Chandler A, Williams JE. Gabapentin, an adjuvant treatment for neuropathic pain in a cancer hospital. J Pain Symptom Manage 2000;20:82–6. 13. Dirks J, Fredensborg BB, Christensen D, Fomsgaard JS, Flyger H, Dahl JB. A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy. Anesthesiology 2002;97:560–4. 14. Gidal BE, Radulovic LL, Kruger S, Rutecki P, Pitterle M, Bockbrader HN. Interand Intra-subject variability in gabapentin absorption and absolute bioavailability. Epilepsy Res 2000;40:123–7. 15. Al-Zehouri J, al-Madi S, Belal F. Determination of the antiepileptics vigabatrin and gabapentin in dosage forms and biological fluids using Hantzsch reaction. Arzneimittelforschung 2001;51:97–103. 16. Hassan Em, Belal F, Al-Deeb OA, Khalil NY. Spectrofluorimetric determination of vigabatrin and gabapentin in dosage forms and spiked plasma samples through derivatization with 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole. J AOAC Int 2001;84:1017–24. 17. Belal F, Abdine H, Al-Majed A, Khalil NY. Spectrofluorimetric determination of vigabatrin and gabapentin in urine and dosage forms through derivatization with fluorescamine. J Pharm Biomed Anal 2002;27:253–60. 18. Ratnaraj N, Patsalos PN. A high-performance liquid chromatography micromethod for the simultaneous determination of vigabatrin and gabapentin in serum. Ther Drug Monit 1998;20:430–4. 19. Lensmeyer GL, Kempf T, Gidal BE, Wiebe DA. Optimized method for determination of gabapentin in serum by high performance liquid chromatography. Ther Drug Monit 1995;17:251–8. 20. Wad N, Kramer G. Sensitive high-performance liquid chromatographic method with fluorometric detection for the simultaneous determination of gabapentin and vigabatrin in serum and urine. J Chromatogr B Biomed Sci Appl 1998;705:154–8. 21. Ifa DR, Falci M, Moraes ME, Bezerra FA, Moraes MO, de Nucci G. Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study. J Mass Spectrom 2001;36:188–94. 22. Forrest G, Sills GJ, Leach JP, Brodie MJ. Determination of gabapentin in plasma by high-performance liquid chromatography. J Chromatogr B Biomed Appl 1996;681:421–5. 23. Garcia LL, Shihabi ZK, Oles K. Determination of gabapentin in serum by capillary electrophoresis. J Chromatogr B Biomed Appl 1995;669:157–62. 24. Kushnir MM, Crossett J, Brown PI, Urry FM. Analysis of gabapentin in serum and plasma by solid-phase extraction and gas chromatography-mass spectrometry for therapeutic drug monitoring. J Anal Toxicol 1999;23:1–6. 25. Wolf CE, Saady JJ, Pokis A. Determination of gabapentin in serum using solid-phase extraction and gas-liquid chromatography. J Anal Toxicol 1996; 20:498–501.

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عنوان ژورنال:
  • Clinical chemistry

دوره 49 7  شماره 

صفحات  -

تاریخ انتشار 2003